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kyoto encyclopedia of genes and genomes (kegg) pathways  (PathView Systems Ltd)

 
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    PathView Systems Ltd kyoto encyclopedia of genes and genomes (kegg) pathways
    Kyoto Encyclopedia Of Genes And Genomes (Kegg) Pathways, supplied by PathView Systems Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/kyoto+encyclopedia+of+genes+and+genomes+pathways/pmc11876959-66-0-18?v=PathView+Systems+Ltd
    Average 90 stars, based on 1 article reviews
    kyoto encyclopedia of genes and genomes (kegg) pathways - by Bioz Stars, 2026-07
    90/100 stars

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    Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis of the top 3,000 differentially expressed genes comparing the infarcted myocardium from WT and Ffar4KO hearts was performed using Pathview. ( A ) The AMPK Signaling pathway was downregulated in the Ffar4KO infarcted myocardium. Downregulated genes included. Ampk , Adra1a , Pgc1α , Acc2 , Cpt1 , Pfk2 , and Fbp . ( B ) The Cellular Senescence pathway was upregulated in the Ffar4KO infarcted myocardium. Upregulated genes included: Tgfb , Igfbp3 , Pai-1 (all 3 part of the senescence associated secretory pathway, SASP), as well as, p15 , p21 , CycA , CycB , CycD , Cdk1 , Cd64/6 , Gadd45 , CaM , Ras , E2F , FoxM1 , and B-Myb .

    Journal: bioRxiv

    Article Title: Free fatty acid receptor 4 in cardiac myocytes ameliorates ischemic cardiomyopathy

    doi: 10.1101/2024.04.12.589280

    Figure Lengend Snippet: Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis of the top 3,000 differentially expressed genes comparing the infarcted myocardium from WT and Ffar4KO hearts was performed using Pathview. ( A ) The AMPK Signaling pathway was downregulated in the Ffar4KO infarcted myocardium. Downregulated genes included. Ampk , Adra1a , Pgc1α , Acc2 , Cpt1 , Pfk2 , and Fbp . ( B ) The Cellular Senescence pathway was upregulated in the Ffar4KO infarcted myocardium. Upregulated genes included: Tgfb , Igfbp3 , Pai-1 (all 3 part of the senescence associated secretory pathway, SASP), as well as, p15 , p21 , CycA , CycB , CycD , Cdk1 , Cd64/6 , Gadd45 , CaM , Ras , E2F , FoxM1 , and B-Myb .

    Article Snippet: Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis using Pathview identified numerous KEGG pathways that were significantly altered in the Ffar4KO infarcted myocardium.

    Techniques: